刘兴国 Liu Xingguo

中国科学院广州生物医药与健康研究院

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刘兴国,男,博士,研究员,博士生导师,国家自然科学基金优秀青年获得者,中科院""百人计划""获得者,广东省自然科学杰出青年基金获得者,广东省特支计划中青年科技领军人才,2016年干细胞青年研究员奖和国际生物物理学会""2011 Young Bioenergeticist Award""获得者(每年只有一人获此奖项),国际学术杂志Frontiers in Genetics of Aging、Int J Stem Cell Res Transp、Biophysics编委,Plos One、FEBS Letters、Cell Regeneration、Bioresource Technol、Biotechnol Bioeng审稿人。2007年1月获得清华大学博士学位,2007-2010年在美国Thomas Jefferson University做博士后研究,2010年至今在中国科学院广州生物医药与健康研究院担任研究员、博导。以第一或通讯作者身份在Cell Metabolism、Hepatology、EMBO J、Cell Death & Diff、Mol Cell等国际杂志上发表22篇论文,申请专利9项(其中1项PCT)。承担973项目、国家自然科学基金、中国科学院战略性先导科技专项等10项国家和地方的基金支持,9次在国际学术会议上做大会特邀报告,任第9届亚洲线粒体研究与医学国际研讨会组委会成员。

 

代表性论文:

1. Zhongfu Ying, Keshi Chen, Lingjun Zheng, Yi Wu, Linpeng Li, Rui Wang, Qi Long, Liang Yang,  Jingyi Guo, Deyang Yao, Yong Li, Feixiang Bao, Ge Xiang, Jinglei Liu, Qiaoying Huang, Zhiming Wu, Andrew Paul Hutchins, Duanqing Pei and Xingguo Liu*. Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming. Cell Metabolism. 2016, 23(1): 220-226.

2. Shengbiao Li, Jingyi Guo, Zhongfu Ying , Shen Chen, Liang Yang, Keshi Chen, Qi Long, Dajiang Qin, Duanqing Pei, Xingguo Liu*. Valproic Acid-Induced Hepatotoxicity in Alpers Syndrome Is Associated With Mitochondrial Permeability Transition Pore Opening-Dependent Apoptotic Sensitivity in an Induced Pluripotent Stem Cell Model. Hepatology. 2015, 61(5): 1730-1739.

3. Ge Xiang, Liang Yang, Qi Long, Keshi Chen, Haite Tang, Yi Wu, Zihuang Liu, Yanshuang Zhou, Juntao Qi, Lingjun Zheng, Wenbo Liu, Zhongfu Ying, Weimin Fan, Hongyan Shi, Hongmei Li, Xiaobing Lin, Mi Gao, Jinglei Liu, Feixiang Bao, Linpeng Li, Lifan Duan, Min Li & Xingguo Liu*. BNIP3L-dependent Mitophagy Accounts for Mitochondrial Clearance during SKO-induced Somatic Cell Reprogramming. Autophagy. 2017, 13(9): 1543-1555.

4. Keshi Chen, Qi Long, Tao Wang, Danyun Zhao, Yanshuang Zhou, Juntao Qi, Yi Wu, Shengbiao Li, Chunlan Chen, Xiaoming Zeng, Jianguo Yang, Zisong Zhou, Weiwen Qin, Xiyin Liu, Yuxing Li, Yingying Li, Xiaofen Huang, Dajiang Qin, Jiekai Chen, Guangjin Pan, Hans R Schöler, Guoliang Xu, Xingguo Liu*, Duanqing Pei*. FRAP screening identifies Gadd45a as a heterochromatin relaxer that enhances iPSC generation. EMBO Reports. 2016, 17(11): 1641-1656. 

5. Xingguo Liu, David Weaver, Orian Shirihai and György Hajnóczky. Mitochondrial ""kiss-and-run"": interplay between mitochondrial motility and fusion fission dynamics. EMBO J. 2009, 28 (20): 3074-3089."

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